Side
Effects
This medication is generally well tolerated. Dry mouth, headache, increased
sweating, nausea/vomiting, constipation, anxiety, fatigue and blurred vision
may occur. If these effects persist or worsen, notify your doctor. Report promptly:
unusual weight loss or gain, palpitations, agitation, trouble sleeping. Unlikely
but report promptly: tremor, dizziness, fainting, mood changes, slowed movements,
difficulty urinating, decreased sex drive, drowsiness. Very unlikely but report
promptly: seizures, mental problems, fever, muscle aches, yellowing of the
eyes or skin. In the unlikely event you have an allergic reaction to this drug,
seek medical attention immediately. Symptoms may include trouble breathing,
rash, itching, swelling, or severe dizziness. If you notice other effects not
listed above, contact your doctor or pharmacist.
Precautions
Before taking bupropion, tell your doctor if you have: history of seizures
or head injury or brain tumor, heart disease, liver or kidney disease, eating
disorder, diabetes, alcohol dependence, any allergies, the intent to quit
smoking. Because of the possibility this drug will make you dizzy and affect
coordination, do not drive or operate machinery until you get used to the
drug's effects. Limit or avoid consumption of alcoholic beverages; alcohol
can increase your risk of seizures. Chronic alcohol users who suddenly stop
the intake of alcohol while taking bupropion may increase the risk of having
seizures. Suddenly stopping certain tranquilizers (e.g., diazepam, chlordiazepoxide)
is not recommended because doing so may increase the risk of having seizures.
Elderly patients may be more sensitive to the effects of this drug. Tell
your doctor if you are pregnant or plan to become pregnant before taking
this drug. This drug passes into breast milk. Because of the potential risk
to the infant, breast-feeding while using this drug is not recommended. Consult
your doctor before breast-feeding.
Drug Interactions
Before taking bupropion tell your doctor of all nonprescription and prescription
medications you may use especially: MAO inhibitors (e.g., isocarboxazid,
phenelzine, tranylcypromine, pargyline, selegiline, linezolid, furazolidone),
levodopa, ritonavir, corticosteroids (e.g. prednisone), sedatives, adrenaline-like
stimulants (e.g., ephedrine), products containing nicotine (e.g., patches
or gum). Also report use of drugs which might increase seizure risk (decrease
seizure threshold) such as: phenothiazines (e.g., chlorpromazine), tricyclic
antidepressants (e.g., amitriptyline), isoniazid (INH), theophylline. Excess
caffeine intake can increase the chance of seizures with this drug. Check
all nonprescription/prescription drug labels for caffeine. Consult your doctor
or pharmacist. A certain product used to help quit smoking contains bupropion.
Do not take that product while using this one. Do not start or stop any medicine
without doctor or pharmacist approval.
Overdose
If overdose is suspected, contact your local poison control center or emergency
room immediately. Symptoms of overdose may include seizures, hallucinations,
rapid heart rate, and loss of consciousness.
Notes
Do not allow anyone else to take this medication.
Missed Dose
Take any missed dose as soon as possible but not if it is within 4 hours of
the next dose. If it is time for the next dose, skip the missed dose and
resume your regular schedule. Do not "double-up" the dose.
Storage
Store at room temperature and keep away from moisture and sunlight. Do not
store in the bathroom.
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