Side effects
Zyban is generally well tolerated. Dry mouth, headache, increased sweating, constipation,
anxiety and fatigue may occur. If these effects persist or worsen, notify your
doctor.
Precautions
Before taking bupropion tell your doctor if you have a history of seizures,
head injury, brain tumor; heart, liver or kidney disease, an eating disorder
or any mental conditions, diabetes or if you have any allergies. Limit or
avoid consumption of alcoholic beverages; alcohol can increase your risk
of seizures. Chronic alcohol users who suddenly stop the intake of alcohol
while taking bupropion may increase the risk of having seizures. Suddenly
stopping certain tranquilizers (e.g., diazepam, chlordiazepoxide) is not
recommended because doing so may increase the risk of having seizures. Elderly
patients may be more sensitive to the effects of this drug. Tell your doctor
if you are pregnant or plan to become pregnant before taking this drug. This
drug is excreted into breast milk. Because of the potential risk to the infant,
breast-feeding while using this drug is not recommended. Consult your doctor
before breast-feeding.
Drug interactions
Before taking bupropion tell your doctor of all nonprescription and prescription
medications you may use especially MAO inhibitors (e.g., isocarboxazid, phenelzine,
tranylcypromine, pargyline, selegiline, furazolidone), levodopa, theophylline,
corticosteroids (e.g., prednisone), seizure medications, sedatives, ritonavir,
tranquilizers/psychiatric drugs (e.g., chlorpromazine), other antidepressants
(e.g., amitriptyline), salicylates (e.g., aspirin, salsalate), isoniazid,
chlolinesterase inhibitors (e.g., tacrine, donepezil), morphine, and adrenaline-like
drugs (e.g., pseudoephedrine). Excess caffeine intake can increase the chance
of seizures with this drug. Check all nonprescription/prescription drug labels
for caffeine. Consult doctor or pharmacist. A certain product used to help
quit smoking contains bupropion. Do not take that product while using this
one.
Notes
Do not allow anyone else to take Zyban.
Miss dose
Take any missed dose as soon as possible but not if it is within 8 hours of
the next dose. If it is time for the next dose, skip the missed dose and
resume your regular schedule. Do not "double up" the dose.
Storage
Store at room temperature and keep away from moisture and sunlight. Keep this
and all medications out of the reach of children.
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